Peptic Ulcer Research Today is a free monthly online journal that collates and summarizes the latest research about Peptic Ulcer, including details on helicobacter pylori, diet, symptoms, treatment.

Medical management of acid-peptic disorders of the stomach.

Eswaran S, Roy MA

Portland Gastroenterology Associates, 1200 Congress Street, Suite 300 Portland, ME 04102-2129, USA.

In the past 30 years, medicine has witnessed an unprecedented evolution in acid-peptic disorder management, fueled by major advances in our understanding of the physiology of acid secretion and the gastric mucosal barrier. The other pivotal development in understanding these disorders has been the recognition of Helicobacter pylori's role in the pathophysiology of peptic ulcer disease,chronic gastritis, and even gastric malignancy. This evolution continues as H pylori wanes in significance, and medicine is challenged by treating iatrogenic conditions brought on by ulcerogenic anti-inflammatory drugs. Following a description of the relevant physiology and biochemistry of gastric acid secretion and the gastric mucosal barrier, this article describes the current medicinal arsenal available to treat acid-peptic disorders of the stomach.

Published 5 September 2005 in Surg Clin North Am, 85(5): 895-906, v.
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